{"schema":"sb.node.v1","id":"sb:e/7e334b5071e5b4486106b1fd","kind":"entity","label":{"text":"kras","locale":"en"},"identity":{"anchor":"label:en:kras","strength":"label"},"asOf":{"knowledgeCutoff":"2026-11-10T23:26:12.528504+00:00","releaseId":"sb-8792b91ece33","snapshot":"deploy cb03188cd71ab9aaafd7516efad4097bf188509c"},"lens":{"kind":"public"},"build":{"plane":"projected","builtFrom":["entity_graph.slim.json","entity_receipts (deploy asset)","event_graph.json","truth_records (deploy asset)","corroborated_record.json"],"rule":"node-projection.entity@v1"},"standing":{"evidence":{"supporting":539,"separatePublishers":189,"basis":"documents that mention the subject and the outlets that carried them; a mention is evidence the referent is in use, not evidence about any claim","receiptsOnTopic":{"state":"measured","share":0.761,"named":410,"of":539,"basis":"documents whose own title or summary lead names the subject, over every counted document that mentions it anywhere (the entity graph's measurement); receipts are drawn only from rows whose own title or URL names the subject (the entity graph's subject gate)"}},"admission":{"state":"canonical","kind":"legacy","kindBasis":"seed","reason":"entity graph provenance 'curated'; part of the hand-written seed vocabulary that predates machine promotion; no receipt exists","policy":"promotion (seed vocabulary; no receipt)"},"disposition":{"state":"served","reason":"public record"},"validity":{"from":"2026-03-11","to":"2026-11-09","basis":"first and last day we saw it mentioned; not the subject's own lifetime"},"measurement":{"state":"partial","share":0.071,"blind":["7% of mentions say something specific about it; the rest only name it"]}},"dimensions":{"domains":["oncology"],"activeDays":189,"assertions":{}},"up":[],"upNote":"An entity is a root: it is contained by nothing. Pan out by following R.","children":{"count":7,"byKind":{"observation":7},"withheld":{"state":"withheld","count":5,"reason":"5 receipts withheld: no source link (the same rule the topic record applies)"},"items":[{"id":"sb:o/fcdc1732f8fae063f84e3763","kind":"observation","label":"Parasites Hosts Dis · 2026-11-06 · Toxoplasma gondii GRA16-induced apoptosis in KRAS-mutant colorectal cancer cells is linked to coordinated p53 and PP2A-B55 signaling.","url":"https://doi.org/10.3347/PHD.26050","match":{"surface":"title","basis":"admitted by the entity graph's subject gate (title or URL); the headline names the subject as whole words (the door's on-topic test)"}},{"id":"sb:o/55444371dd869070a2f0bfc5","kind":"observation","label":"Inside Precision Medicine · 2026-11-04 · New Standard-of-Care for KRAS G12C-Mutated Advanced NSCLC","url":"https://www.insideprecisionmedicine.com/topics/oncology/new-standard-of-care-for-kras-g12c-mutated-advanced-nsclc/","match":{"surface":"title","basis":"admitted by the entity graph's subject gate (title or URL); the headline names the subject as whole words (the door's on-topic test)"}},{"id":"sb:o/2dd1b5017b4213b7883fbb91","kind":"observation","label":"Respirol Case Rep · 2026-11-02 · KRAS G12Y Causing a False-Positive KRAS G12C Result With an Indistinguishable PCR Pattern in Lung Adenocarcinoma.","url":"https://doi.org/10.1002/rcr2.70805","match":{"surface":"title","basis":"admitted by the entity graph's subject gate (title or URL); the headline names the subject as whole words (the door's on-topic test)"}},{"id":"sb:o/1d10fcf1acde5a15686acd36","kind":"observation","label":"The Medical News · 2026-10-31 · New strategy identified for overcoming resistance to KRAS-targeted cancer therapies","url":"https://www.news-medical.net/news/20261030/New-strategy-identified-for-overcoming-resistance-to-KRAS-targeted-cancer-therapies.aspx","match":{"surface":"title","basis":"admitted by the entity graph's subject gate (title or URL); the headline names the subject as whole words (the door's on-topic test)"}},{"id":"sb:o/2cf52f9e04c0e282e5206e5f","kind":"observation","label":"J Hematol Oncol · 2026-10-30 · KRAS in pancreatic cancer: from molecular biology to transformative therapeutics.","url":"https://doi.org/10.1186/s13045-026-01863-x","match":{"surface":"title","basis":"admitted by the entity graph's subject gate (title or URL); the headline names the subject as whole words (the door's on-topic test)"}},{"id":"sb:o/f8c7ae6fae89a27e58362784","kind":"observation","label":"Targeted Oncology · 2026-10-30 · Dr Wainberg on RASolute 302: Daraxonrasib Across KRAS Variants","url":"https://www.targetedonc.com/view/dr-wainberg-on-rasolute-302-daraxonrasib-across-kras-variants-pancreatic-cancer","match":{"surface":"title","basis":"admitted by the entity graph's subject gate (title or URL); the headline names the subject as whole words (the door's on-topic test)"}},{"id":"sb:o/4708c8d51cdf0517b7614b9e","kind":"observation","label":"Cancer Med · 2026-10-30 · Divergent Roles of PIK3C3 in KRAS-Wild-Type and KRAS-Mutant Advanced Colorectal Cancer: Implications for 5-Fluorouracil Sensitivity and Prognosis.","url":"https://doi.org/10.1002/cam4.72434","match":{"surface":"title","basis":"admitted by the entity graph's subject gate (title or URL); the headline names the subject as whole words (the door's on-topic test)"}}],"cursor":null,"order":"newest first; we keep the 7 newest receipts for this entity whose own title or URL (the entity graph's subject gate) names it; each says which in match. Its other observations are counted in standing.evidence.supporting but are not addressable in v1"},"relations":{"count":13,"byKind":{"claim":3,"co-mentioned":10},"items":[{"id":"sb:p/bbd716ae4bdc4407590cb184","kind":"claim","label":"Dr Skoulidis on Divarasib vs Sotorasib or Adagrasib in KRAS G12C–Mutated NSCLC - OncLive — single source","role":"named-in","relationKind":"claim","members":1},{"id":"sb:p/0da6a7c99156c5d1839d097c","kind":"claim","label":"How Does Divarasib Compare With Other KRAS Inhibitors in NSCLC? - Targeted Oncology — single source","role":"named-in","relationKind":"claim","members":1},{"id":"sb:p/a7f818fbc9f881b7d33ec7c4","kind":"claim","label":"Sotorasib plus panitumumab extends progression-free survival in KRAS G12C-mutant colorectal cancer — could not check","role":"named-in","relationKind":"claim","members":1},{"kind":"relation","label":"co-mentioned with colorectal cancer (195 documents)","role":"co-mentioned","relationKind":"co-mentioned","members":2,"id":"sb:r/a2b974f1c240c095cd3e4442"},{"kind":"relation","label":"co-mentioned with lung cancer (139 documents)","role":"co-mentioned","relationKind":"co-mentioned","members":2,"id":"sb:r/1715d936aa939769f1c32a6b"},{"kind":"relation","label":"co-mentioned with g12d (96 documents)","role":"co-mentioned","relationKind":"co-mentioned","members":2,"id":"sb:r/3c25303808c8dcd5bc600407"},{"kind":"relation","label":"co-mentioned with immunotherapy (76 documents)","role":"co-mentioned","relationKind":"co-mentioned","members":2,"id":"sb:r/2ad88300301226428172cfc9"},{"kind":"relation","label":"co-mentioned with kras-mutant (67 documents)","role":"co-mentioned","relationKind":"co-mentioned","members":2,"id":"sb:r/01eda8a71d27fc6bc646c93f"},{"kind":"relation","label":"co-mentioned with egfr (56 documents)","role":"co-mentioned","relationKind":"co-mentioned","members":2,"id":"sb:r/e48ba47d5ab3e22994704e75"},{"kind":"relation","label":"co-mentioned with cancer cells (51 documents)","role":"co-mentioned","relationKind":"co-mentioned","members":2,"id":"sb:r/5ffb1e1f855a004e19c40842"}],"cursor":"c1.eyJpZCI6InNiOmUvN2UzMzRiNTA3MWU1YjQ0ODYxMDZiMWZkIiwibCI6InJlbGF0aW9ucyIsIm8iOjEwLCJrIjpudWxsLCJhIjoiMjAyNi0xMS0xMFQyMzoyNjoxMi41Mjg1MDQrMDA6MDAifQ","order":"situations first, then claims (the subject's own maintained record, then site-wide corroborated clusters; each label ends with its standing), then co-mentions by shared documents, descending. Co-mentions are the ten strongest the entity graph keeps per entity"},"edge":{"state":"continues"},"links":{"rest":"/api/v1/node/e/7e334b5071e5b4486106b1fd","mcp":"traverse {\"id\":\"sb:e/7e334b5071e5b4486106b1fd\"}","page":"/entity/kras/"},"limits":{"levelsPerCall":1,"pageSize":10,"maxPageSize":50,"membersMax":50,"statement":"One level per call: depth is 1 and only 1, and there is no whole-graph dump. pageSize 1-50 (default 10); a page limit is a cursor, never an edge. Members are listed up to 50. At most 60 traverse calls a minute per caller (runaway-loop protection, not a meter). One knowledge cutoff is served: the deploy's."},"actions":[{"verb":"unfold","lit":true,"effect":"read","layer":"free-record","call":"traverse {\"id\":\"sb:e/7e334b5071e5b4486106b1fd\",\"level\":\"children\"}"},{"verb":"fold","lit":true,"effect":"read","layer":"free-record","call":"traverse {\"id\":\"sb:e/7e334b5071e5b4486106b1fd\"}"},{"verb":"panOut","lit":false,"effect":"read","layer":"free-record","reason":"An entity is a root: it is contained by nothing. Pan out by following R."},{"verb":"follow","lit":true,"effect":"read","layer":"free-record","call":"traverse {\"id\":\"sb:e/7e334b5071e5b4486106b1fd\",\"level\":\"relations\"}"},{"verb":"receipts","lit":false,"effect":"read","layer":"free-record","reason":"receipts are the observations below this node; unfold to reach them"},{"verb":"edge","lit":true,"effect":"read","layer":"free-record","call":"traverse {\"id\":\"sb:e/7e334b5071e5b4486106b1fd\"}"},{"verb":"asOf","lit":false,"effect":"read","layer":"free-record","reason":"v1 serves one knowledge cutoff, this deploy's; walking an earlier cutoff needs retained history, which v1 does not keep"},{"verb":"switchObserver","lit":false,"effect":"read","layer":"free-record","reason":"the public record is the same for every observer; traversal through a Watch's lens is not served in v1"},{"verb":"readOriginal","lit":false,"effect":"read","layer":"free-record","reason":"no translation is applied on this node; every label is the source's own text"},{"verb":"save","lit":false,"effect":"watch-declaration","layer":"watch","reason":"saving applies to a configured Watch; configure one around this node first (free), then save it"},{"verb":"deliver","lit":false,"effect":"watch-declaration","layer":"watch","reason":"delivery applies to a saved Watch"},{"verb":"format","lit":false,"effect":"watch-declaration","layer":"watch","reason":"output format applies to a saved Watch"},{"verb":"deltaR","lit":false,"effect":"read","layer":"watch","reason":"Delta R needs a saved Watch with a previous reading"},{"verb":"read","lit":false,"effect":"read","layer":"one-time-read","reason":"one-time Reads are not offered through this door; use ask"}]}